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Published at November 26Emergenet: A Digital Twin of Sequence Evolution for Scalable Emergence Risk Assessment of Animal Influenza A Strains
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Released Date: November 26, 2024
Authors: Kevin Yuanbo Wu1, Jin Li1, Aaron Esser-Kahn2, Ishanu Chattopadhyay1
Aff.: 1Department of Medicine, University of Chicago, IL, USA; 2Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, USA
| Season | WHO Recommendation | Enet Recommendation, Cluster 1 | Enet Recommendation, Cluster 2 | Enet Recommendation, Single Cluster | WHO Error | Enet Error | Enet Error Single |
| 2003 | A/New Caledonia/20/99 | A/HaNoi/2143/2001 | A/HaNoi/2143/2001 | A/HaNoi/2143/2001 | 7.3 | 3.0 | 3.0 |
| 2004 | A/New Caledonia/20/99 | A/HaNoi/2546/2002 | A/HaNoi/2704/2002 | A/HaNoi/2546/2002 | 11.2 | 8.8 | 10.8 |
| 2005 | A/New Caledonia/20/99 | A/Michigan/1/2003 | A/Michigan/1/2003 | A/Michigan/1/2003 | 8.7 | 5.8 | 5.8 |
| 2006 | A/New Caledonia/20/99 | A/Malaysia/25531/2003 | A/Auckland/619/2005 | A/Malaysia/25531/2003 | 12.9 | 9.7 | 10.6 |
| 2007 | A/New Caledonia/20/99 | A/Malaysia/1652509/2006 | A/Malaysia/25531/2003 | A/Malaysia/34291/2006 | 21.6 | 15.1 | 14.9 |
| 2008 | A/Solomon Islands/3/2006 | A/Malaysia/1715991/2007 | A/Canada/0379/2007 | A/New_York/08/2007 | 11.1 | 4.7 | 12.7 |
| 2009 | A/Brisbane/59/2007 | A/California/28/2007 | A/Vietnam/100/2008 | A/California/28/2007 | 402.0 | 401.2 | 402.1 |
| 2010 | A/California/7/2009 | A/Hong_Kong/H090-751-V3 | A/Hawaii/02/2008 | A/Hong_Kong/H090-751-V3 | 11.7 | 4.3 | 8.0 |
| 2011 | A/California/7/2009 | A/Guangdong/1250/2009 | A/Kenya/1329/2010 | A/Guangdong/1250/2009 | 10.5 | 6.7 | 6.7 |
| 2012 | A/California/7/2009 | A/Singapore/GP81/2011 | A/Chongqing-Yuzhong/SWL11307/2009 | A/Scotland/ Inverness_10/2009 | 12.6 | 6.9 | 6.9 |
| 2013 | A/California/7/2009 | A/Virginia/07/2012 | A/Kenya/CDC-KNH-028/2010 | A/Singapore/GP4215/2010 | 13.3 | 6.5 | 9.2 |
| 2014 | A/California/7/2009 | A/England/358/2013 | A/India/P1114854/2011 | A/Cruz Alta/ LACENRS-129/2012 | 13.8 | 4.3 | 2.5 |
| 2015 | A/California/7/2009 | A/North_Carolina/07/2013 | A/shandong-zhifu/SWL1105/2014 | A/North_Carolina/07/2013 | 14.9 | 4.1 | 4.1 |
| 2016 | A/California/7/2009 | A/Colombia/1457/2015 | A/India/1399/2015 | A/Cruz Alta/ LACENRS-129/2012 | 16.8 | 4.2 | 5.0 |
| 2017 | A/Michigan/45/2015 | A/Ivanovo/CRIE-73/2016 | A/Albania/6485/2016 | A/Ivanovo/CRIE-73/2016 | 5.5 | 4.5 | 4.5 |
| 2018 | A/Michigan/45/2015 | A/Qatar/16-VI-17-0046212/2017 | A/Chongqing-Yuzhong/SWL1453/2017 | A/Texas/28/2016 | 8.8 | 3.9 | 5.9 |
| 2019 | A/Michigan/45/2015 | A/California/145/2017 | A/California/145/2017 | A/California/145/2017 | 11.2 | 6.3 | 6.3 |
| 2020 | A/Brisbane/02/2018 | A/Shanghai/192/2018 | A/Germany/9054/2019 | A/Nepal/19FL3860/2019 | 28.9 | 23.2 | 23.7 |
| 2021 | A/Victoria/2570/2019 | A/Yaroslavl/138/2020 | A/Ontario/RV1058/2019 | A/Qatar/16-VI-19-0068514/2019 | 11.6 | 12.0 | 11.1 |
| 2022 | A/Victoria/2570/2019 | A/Netherlands/10253/2020 | A/India/PUN-NIV323483/2021 | A/Mecklenburg-Vorpommern/2/2020 | 9.9 | 3.7 | 11.3 |
| 2023 | A/Sydney/5/2021 | A/Pakistan/GIHSN/ ICT/826/2023 | A/NIIGATA/922/2019 | A/Pakistan/GIHSN/ ICT/826/2023 | -1 | -1 | -1 |