notesum.ai

Published at November 22

Detecting Hallucinations in Virtual Histology with Neural Precursors

eess.IV

cs.CV

Released Date: November 22, 2024

Authors: Ji-Hun Oh¹, Kianoush Falahkheirkhah¹, Rohit Bhargava²

Aff.: ¹University of Illinois Urbana-Champaign, Urbana, IL, USA; ²CZ Biohub Chicago, LLC, Chicago, IL, USA

Arxiv: http://arxiv.org/abs/2411.15060v1

SRS-to-HE

HO342-to-CD3

HO342-to-CD8

HE-to-ER

HE-to-HER2

HE-to-PR

HE-to-Ki67

Method

Pix2PixHD

VSGD+pNCE

Pix2PixHD

VSGD+pNCE

Pix2PixHD

VSGD+pNCE

CycleGAN

CUT

CycleGAN

CUT

CycleGAN

CUT

CycleGAN

CUT

Avg.

GAN-based anomaly detection

ALOCC

-33.22_±10.3

-0.38_±20.83

-30.8_±4.83

15.61_±16.96

-7.46_±9.05

15.69_±19.96

2.99_±44.22

0.56_±26.08

11.78_±24.42

3.16_±26.15

9.39_±46.25

-25.88_±12.54

24.8_±20.42

3.95_±29.42

-0.7

ALAD

-6.8_±8.99

-7.02_±14.97

-3.86_±12.31

2.5_±22.81

-3.8

f-AnoGAN_res.

3.85_±7.62

-4.13_±7.12

4.76_±3.41

8.56_±5.92

3.26

NHP ablations over KNN setup

NHP (

\gamma=0

)

40.7_±8.45

36.66_±5.84

40.29_±3.38

49.33_±16.86

24.2_±5.27

30.65_±14.77

68.03_±3.09

56.42_±5.32

50.14_±5.1

42.79_±8.5

68.64_±1.93

53.99_±5.3

66.74_±3.52

40.91_±18.87

47.82

NHP (

q=0

)

21.44_±13.01

18.33_±10.78

50.49_±1.08

47.23_±15.17

43.62_±5.12

30.88_±13.87

47.71_±3.83

41.91_±14.59

42.19_±6.69

24.41_±7.78

57.37_±3.96

41.34_±10.25

57.41_±4.6

37.61_±22.02

40.14

NHP (linear)

40.7_±8.45

36.66_±5.84

50.59_±4.81

49.37_±15.65

42.56_±7.99

33.31_±15.99

70.51_±2.61

61.6_±6.9

50.6_±5.37

42.93_±9.29

68.6_±1.98

57.24_±4.94

67.14_±3.69

50.36_±17.35

51.58

NHP ablations by different distance measures

NHP (OtB)

13.07_±9.27

34.8_±8.88

40.54_±5.57

39.89_±13.85

29.36_±9.69

27.87_±12.09

61.11_±2.16

49.51_±4.34

45.03_±4.26

35.05_±9.32

63.88_±2.57

51.49_±4.93

61.69_±3.05

38.66_±15.99

42.28

NHP (Res.)

12.02_±17.01

2.75_±17.28

53.06_±1.54

49.25_±16.24

47.66_±3.04

32.52_±18.07

37.68_±7.54

30.09_±19.75

46.38_±7.6

22.39_±8.58

48.03_±6.4

31.7_±21.86

61.11_±5.43

47.47_±15.43

37.29

NHP (GMM)

49.04_±5.54

28.73_±9.94

41.61_±3.99

49.53_±16.94

33.57_±6.51

32.04_±14.03

66.71_±2.01

58.27_±5.13

50.74_±5.34

43.93_±8.18

68.51_±2.36

54.75_±6.52

65.42_±3.14

42.17_±22.87

48.93

NHP

49.32_±5.51

37.24_±5.74

51.07_±4.55

49.45_±15.44

45.65_±6.09

33.5_±15.94

69.25_±2.86

62.15_±6.31

51.0_±5.47

43.38_±8.93

68.87_±1.87

57.76_±4.51

67.0_±3.63

47.91_±20.45

52.40